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Abstract:
Monitoring the strongly regulated sodium content in vivo is of great interest for a variety of diseases. Imaging this nucleus is difficult due to its low concentration and fast relaxation. Using an ultra-high field scanner at 9.4 Tesla, a dedicated RF coils and the efficient Twisted Projection Imaging sequence, 2mm nominal isotropic sodium images of the human brain were acquired. Comparison with an MP-RAGE image shows the fine anatomical details, while a 4T comparison shows the great SNR improvement.