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  Comparing SMB Chromatography with Low Capacity/High Selectivity and High Capacity/Low Selectivity Chiral Stationary Phases

Kaspereit, M., Backovska, V., Skavrada, M., Jandera, P., & Seidel-Morgenstern, A. (2001). Comparing SMB Chromatography with Low Capacity/High Selectivity and High Capacity/Low Selectivity Chiral Stationary Phases. Poster presented at PREP - 14th International Symposium on Preparative/Process Chromatography, Washington, D.C., USA.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-A14C-2 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-A14D-F
Genre: Poster

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 Creators:
Kaspereit, M.1, Author           
Backovska, V.2, Author
Skavrada, M.2, Author
Jandera, P.2, Author
Seidel-Morgenstern, A.1, 3, Author           
Affiliations:
1Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738150              
2University of Pardubice, Faculty of Chemical Technology, nám. Cs. legií 565, 532 10 Pardubice, Czech Republic, ou_persistent22              
3Otto-von-Guericke-Universität Magdeburg, External Organizations, ou_1738156              

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 Abstract: Simulated moving bed (SMB) chromatography is increasingly applied in the pharmaceutical industry. Numerous chiral stationary phases (CSPs) exist for enantioseparations. The adsorption behavior of the enantiomers can differ significantly on these CSPs (depending on system, mobile phase composition, adsorption mechanisms, ...). Frequently several CSPs are available to perform the same separation. Objective of this work is to examine the impact of the adsorption equilibrium functions on the productivity in enantioseparations by SMB chromatography for different combinations of CSP/mobile phase.

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Language(s): eng - English
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 Publication Status: Not specified
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 Identifiers: eDoc: 244817
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Title: PREP - 14th International Symposium on Preparative/Process Chromatography
Place of Event: Washington, D.C., USA
Start-/End Date: 2001-05-13 - 2001-05-16

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