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  Comparison of network-based pathway analysis methods

Papin, J. A., Stelling, J., Price, N. D., Klamt, S., Schuster, S., & Palsson, B. O. (2004). Comparison of network-based pathway analysis methods. Trends in Biotechnology, 22(8), 400-405. doi:10.1016/j.tibtech.2004.06.010.

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Papin, J. A.1, Autor
Stelling, J.2, Autor           
Price, N. D.1, Autor
Klamt, S.2, Autor           
Schuster, S.3, Autor
Palsson, B. O.3, Autor
Affiliations:
1University of California, Department of Bioengineering, S. Diego, United States , ou_persistent22              
2Systems Biology, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738155              
3Jena University, Department of Bioinformatics, Jena, Germany , ou_persistent22              

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 Zusammenfassung: Network-based definitions of biochemical pathways have emerged in recent years. These pathway definitions insist on the balanced use of a whole network of biochemical reactions. Two such related definitions, elementary modes and extreme pathways, have generated novel hypotheses regarding biochemical network function. The relationship between these two approaches can be illustrated by comparing and contrasting the elementary modes and extreme pathways of previously published metabolic reconstructions of the human red blood cell (RBC) and the human pathogen Helicobacter pylori. Descriptions of network properties generated by using these two approaches in the analysis of realistic metabolic networks need careful interpretation. Copyright © 2004 Elsevier Ltd. All rights reserved. [accessed 2013 June 13th]

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Sprache(n): eng - English
 Datum: 2004
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.1016/j.tibtech.2004.06.010
eDoc: 208471
Anderer: 50/04
 Art des Abschluß: -

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Titel: Trends in Biotechnology
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 22 (8) Artikelnummer: - Start- / Endseite: 400 - 405 Identifikator: -