Implementation of analytical methods during upstream processing for an 
influenza A virus production process

Genzel, Y.; Bock, A.; Schwarzer, J.; Dietzsch, C.; Reichl, U.

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Implementation of analytical methods during upstream processing for an influenza A virus production process

Genzel, Y., Bock, A., Schwarzer, J., Dietzsch, C., & Reichl, U. (2007). Implementation of analytical methods during upstream processing for an influenza A virus production process. Talk presented at Vaccine Production: Analytical Methods, Characterisation, Scale-up and Manufacturing. Cologne, Germany. 2007-12-04 - 2007-12-05.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-96ED-4 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0025-0B65-C

Genre: Talk

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Creators:
Genzel, Y.¹, Author
Bock, A.¹, Author
Schwarzer, J.¹, Author
Dietzsch, C.^{1, 2, 3}, Author
Reichl, U.^{1, 4}, Author

Affiliations:
1Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738140
2Dresden University of Technology,, persistent:22
3Lehrstuhl für Bioverfahrenstechnik, Dresden, persistent:22
4Otto-von-Guericke-Universität Magdeburg, ou_1738156

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Abstract: When looking at upstream processing for influenza A virus production thorough analytics can help to identify adequate process conditions. Typically different cell lines, media , virus subtypes and bioreactors are compared. How the use of comprehensive data sets comprising on-line data, cell numbers, virus titers and extracellular metabolites (carbon & gln metabolism, amino acids) can be used for process optimization will be discussed

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Dates: Created: 2007

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Identifiers: eDoc: 332933
Other: GenzelBockSchwarzerDietzschReichl2007

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Title: Vaccine Production : Analytical Methods, Characterisation, Scale-up and Manufacturing

Place of Event: Cologne, Germany

Start-/End Date: 2007-12-04 - 2007-12-05

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