English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  The future of technologies for personalised medicine

Harvey, A., Brand, A., Holgate, S. T., Kristiansen, L. V., Lehrach, H., Palotie, A., et al. (2012). The future of technologies for personalised medicine. New Biotechnology, 29(6), 625-633. doi:10.1016/j.nbt.2012.03.009.

Item is

Files

show Files
hide Files
:
Harvey.pdf (Publisher version), 506KB
Name:
Harvey.pdf
Description:
-
OA-Status:
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
2012
Copyright Info:
2012 Elsevier B.V. All rights reserved.
License:
-

Locators

show

Creators

show
hide
 Creators:
Harvey, Alison1, Author
Brand, Angela2, 3, Author
Holgate, Stephen T.2, 4, Author
Kristiansen, Lars V.5, Author
Lehrach, Hans6, Author           
Palotie, Aarno2, 7, 8, Author
Prainsack, Barbara2, 9, Author
Affiliations:
1Finchley Court, Norwich, UK, ou_persistent22              
2 Scientific Committee for the ESF Forward Look on Personalised Medicine for the European Citizen, France, ou_persistent22              
3Institute for Public Health Genomics, Maastricht University, The Netherlands, ou_persistent22              
4Faculty of Medicine, University of Southampton, Southampton, UK, ou_persistent22              
5Biomedical Sciences Unit, the European Science Foundation, Strasbourg, France, ou_persistent22              
6Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, Ihnestr. 63-74, Berlin, ou_1433550              
7Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, ou_persistent22              
8The Wellcome Trust Sanger Institute, Cambridge, UK, ou_persistent22              
9Brunel University, Uxbridge Middlesex, UK, ou_persistent22              

Content

show
hide
Free keywords: Health Information Systems Health Resources Humans Individualized Medicine/*methods/*trends Translational Medical Research
 Abstract: Personalised medicine promises prediction, prevention and treatment of illness that is targeted to individuals' needs. New technologies for detailed biological profiling of individuals at the molecular level have been crucial in initiating the move to personalised medicine; further novel technologies will be necessary if the vision is to become a reality. We will need to develop new technologies to collect and analyse data in a way that is not just linear but integrated (understanding system level functioning) and dynamic (understanding system in flux). Key factors in the development of technologies for personalised medicine are standardisation, integration and harmonisation. For example, the tools and processes for data collection and analysis must be standardised across research sites. Research activity at different sites must be integrated to maximise synergies, and scientific research must be integrated with healthcare to ensure effective translation. There must also be harmonisation between scientific practices in different research sites, between science and healthcare and between science, healthcare and wider society, including the ethical and regulatory frameworks, the prevailing political and cultural ethos and the expectations of patients/citizens.

Details

show
hide
Language(s): eng - English
 Dates: 2012-09-152012
 Publication Status: Issued
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1016/j.nbt.2012.03.009
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: New Biotechnology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Elsevier
Pages: 13 Volume / Issue: 29 (6) Sequence Number: - Start / End Page: 625 - 633 Identifier: -