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  Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go?

Ottenhoff, T. H. M., & Kaufmann, S. H. E. (2012). Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go? PLoS Pathogens, 8(5): e1002607. doi:10.1371/journal.ppat.1002607.

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Genre: Journal Article
Alternative Title : PLoS Pathog.

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PLoS_Pathogens_2012_8_e1002607.pdf (Publisher version), 248KB
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PLoS_Pathogens_2012_8_e1002607.pdf
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Copyright Ottenhoff, Kaufmann. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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 Creators:
Ottenhoff, Tom H. M., Author
Kaufmann, Stefan H. E.1, Author           
Affiliations:
1Department of Immunology, Max Planck Institute for Infection Biology, Max Planck Society, ou_1664146              

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 Abstract: In this review we discuss recent progress in the development, testing, and clinical evaluation of new vaccines against tuberculosis (TB). Over the last 20 years, tremendous progress has been made in TB vaccine research and development: from a pipeline virtually empty of new TB candidate vaccines in the early 1990s, to an era in which a dozen novel TB vaccine candidates have been and are being evaluated in human clinical trials. In addition, innovative approaches are being pursued to further improve existing vaccines, as well as discover new ones. Thus, there is good reason for optimism in the field of TB vaccines that it will be possible to develop better vaccines than BCG, which is still the only vaccine available against TB.

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Language(s): eng - English
 Dates: 2012-05
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 611187
ISI: 000305322900001
DOI: 10.1371/journal.ppat.1002607
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Title: PLoS Pathogens
  Alternative Title : PLoS Pathog.
Source Genre: Journal
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Publ. Info: SAN FRANCISCO : PUBLIC LIBRARY SCIENCE
Pages: - Volume / Issue: 8 (5) Sequence Number: e1002607 Start / End Page: - Identifier: ISSN: 1553-7374