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  Intolerance to neuroleptics and susceptibility for malignant hyperthermia in a patient with proximal myotonic myopathy (PROMM) and schizophrenia

Schneider, C., Gil, F., Schneider, M., Anetseder, M., Kress, W., & Müller, C. (2002). Intolerance to neuroleptics and susceptibility for malignant hyperthermia in a patient with proximal myotonic myopathy (PROMM) and schizophrenia. Neuromuscular Disorders, 12(1), 31-35.

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Genre: Journal Article
Alternative Title : Neuromusc. Disord.

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 Creators:
Schneider, C1, Author
Gil, FP1, Author
Schneider, M1, Author
Anetseder, M1, Author
Kress, W1, Author
Müller, CR1, Author
Affiliations:
1Max Planck Institute of Psychiatry, Max Planck Society, ou_1607137              

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Free keywords: malignant hyperthermia; myotonic dystrophy; atypical neuroleptics; proximal myotonic myopathy; schizophrenia
 Abstract: We report a patient with proximal myotonic myopathy who was treated with neuroleptics because of exacerbating schizophrenia. Under therapy with fluanxol, the patient developed muscle stiffness and oculogyric cramps. Treatment with both amisulpride and olanzapine lead to markedly elevated serum creatine kinase levels. An in-vitro contracture test was positive for halothane. Thus, in patients with all kinds of multisystemic myotonic myopathies, a susceptibility for malignant hyperthermia and intolerance towards neuroleptics should be taken into account. (C) 2002 Elsevier Science B.V. All rights reserve

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Language(s): eng - English
 Dates: 2002-01
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 4209
ISI: 000173054900005
 Degree: -

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Title: Neuromuscular Disorders
  Alternative Title : Neuromusc. Disord.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 12 (1) Sequence Number: - Start / End Page: 31 - 35 Identifier: ISSN: 0960-8966