Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

 
 
DownloadE-Mail
  mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons

Pfaar, H., von Holst, A., Weisenhorn, D., Brodski, C., Guimera, J., & Wurst, W. (2002). mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons. Development Genes and Evolution, 212(1), 43-46.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel
Alternativer Titel : Dev. Genes Evol.

Externe Referenzen

einblenden:

Urheber

einblenden:
ausblenden:
 Urheber:
Pfaar, H1, Autor
von Holst, A1, Autor
Weisenhorn, DMV1, Autor
Brodski, C1, Autor
Guimera, J1, Autor
Wurst, W1, Autor
Affiliations:
1Max Planck Institute of Psychiatry, Max Planck Society, ou_1607137              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Pet-1; Raphe nuclei; brain; serotonin; development
 Zusammenfassung: Here we describe the expression pattern of a previously unknown mouse gene mPet-1. The isolated cDNA codes for an ETS-domain transcription factor of 237 amino acids in length, which is localized to the nucleus. mPet-1 is a member of the winged helix transcription factor gene family like its rat homologue Pet-1 and the human homologue FEV. The start ATG of mPet-1 and the size of the predicted protein are identical to the human FEV. The mPet-1 protein is clearly smaller since it lacks the first 103 N-terminal amino acids of rat Pet-1. mPet-1 is expressed in central serotonergic (5-hydroxytryptaminergic) neurons located in the mes-/metencephalic raphe nuclei from E11 on until adulthood. In these regions mPet-1 expression co- localizes precisely with the serotonin transporter (Sert), which it initially precedes. Interestingly, mPet-1 was not found in neurons transiently expressing Ser

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2002-02
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 4189
ISI: 000174619200006
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Development Genes and Evolution
  Alternativer Titel : Dev. Genes Evol.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 212 (1) Artikelnummer: - Start- / Endseite: 43 - 46 Identifikator: ISSN: 0949-944X