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  Generalized anxiety disorder: comorbidity, comparative biology and treatment

Nutt, D., Ballenger, J., Sheehan, D., & Wittchen, H. (2002). Generalized anxiety disorder: comorbidity, comparative biology and treatment. International Journal of Neuropsychopharmacology, 5(4), 315-325.

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Genre: Journal Article
Alternative Title : Int. J. Neuropsychopharmacol.

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 Creators:
Nutt, DJ, Author
Ballenger, JC, Author
Sheehan, D, Author
Wittchen, HU1, Author
Affiliations:
1Max Planck Institute of Psychiatry, Max Planck Society, ou_1607137              

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Free keywords: antidepressant; comorbidity; generalized anxiety disorder; treatment
 Abstract: Generalized anxiety disorder (GAD) is a severe and chronic anxiety disorder characterized by uncontrollable worrying and somatic anxiety (tension, insomnia and hypervigilance). It is a common condition, with lifetime prevalence rates for DSM-IV GAD in the general population of approx. 5-6% being reported. In addition, like other anxiety disorders, GAD also shows comorbidity with depression and most of the other anxiety disorders. This article reviews data on the prevalence of GAD, its comorbidity with depression, and its social and economic impact, Proposed neurobiological mechanisms for GAD are discussed, since an understanding of these may help in the development of future therapies. Finally, current pharmacological and non-pharmacological treatment options for GAD are reviewed, with particular attention being paid to published clinical-trial dat

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Language(s): eng - English
 Dates: 2002-12
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 4022
ISI: 000180100200005
 Degree: -

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Title: International Journal of Neuropsychopharmacology
  Alternative Title : Int. J. Neuropsychopharmacol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 5 (4) Sequence Number: - Start / End Page: 315 - 325 Identifier: ISSN: 1461-1457