English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Characterization of ancestral chromosome fusion points in the Indian muntjac deer

Hartmann, N., & Scherthan, H. (2004). Characterization of ancestral chromosome fusion points in the Indian muntjac deer. Chromosoma, 112(5), 213-220. doi:10.1007/s00412-003-0262-4.

Item is

Basic

show hide
Genre: Journal Article
Alternative Title : CHROMOSOMA (BER)

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Hartmann, Nils1, Author
Scherthan, Harry2, Author           
Affiliations:
1Max Planck Society, ou_persistent13              
2Dept. of Human Molecular Genetics (Head: Hans-Hilger Ropers), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433549              

Content

show
hide
Free keywords: -
 Abstract: Tandem fusion, a rare evolutionary chromosome rearrangement, has occurred extensively in muntjac karyotypic evolution, leading to an extreme fusion karyotype of 6/7 (female/male) chromosomes in the Indian muntjac. These fusion chromosomes contain numerous ancestral chromosomal break and fusion points. Here, we designed a composite polymerase chain reaction (PCR) strategy which recovered DNA fragments that contained telomere and muntjac satellite DNA sequence repeats. Nested PCR confirmed the specificity of the products. Two-color fluorescence in situ hybridization (FISH) with the repetitive sequences obtained and T2AG3 telomere probes showed co-localization of satellite and telomere sequences in Indian muntjac chromosomes. Adjacent telomere and muntjac satellite sequences were also seen by fiber FISH. These data lend support to the involvement of telomere and GC-rich satellite DNA sequences during muntjac chromosome fusions.

Details

show
hide
Language(s): eng - English
 Dates: 2004-02-04
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 224397
DOI: 10.1007/s00412-003-0262-4
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Chromosoma
  Alternative Title : CHROMOSOMA (BER)
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 112 (5) Sequence Number: - Start / End Page: 213 - 220 Identifier: ISSN: 0009-5915