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  twilight; a Bioconductor package for estimating the local false discovery rate

Scheid, S., & Spang, R. (2005). twilight; a Bioconductor package for estimating the local false discovery rate. Bioinformatics, 21(12), 2921-2922. doi:10.1093/bioinformatics/bti436.

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 Creators:
Scheid, Stefanie1, Author
Spang, Rainer2, Author           
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1Max Planck Society, ou_persistent13              
2Dept. of Computational Molecular Biology (Head: Martin Vingron), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433547              

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 Abstract: Summary: twilight is a Bioconductor compatible package for analysing the statistical significance of differentially expressed genes. It is based on the concept of the local false discovery rate (FDR), a generalization of the frequently used global FDR. twilight implements the heuristic search algorithm for estimating the local FDR introduced in our earlier work. In addition to the raw significance measures, it produces diagnostic plots, which provide insight into the extent of differential expression across genes.

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Language(s): eng - English
 Dates: 2005-04-07
 Publication Status: Issued
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 Identifiers: eDoc: 268483
DOI: 10.1093/bioinformatics/bti436
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Title: Bioinformatics
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Pages: - Volume / Issue: 21 (12) Sequence Number: - Start / End Page: 2921 - 2922 Identifier: ISSN: 1367-4803