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Free keywords:
Amino Acid Sequence; Bacterial Outer Membrane Proteins/ch [Chemistry]; *Bacterial Outer Membrane Proteins/ge [Genetics]; Base Sequence; Cloning, Molecular; Comparative Study; DNA, Bacterial/ge [Genetics]; *Genes, Structural, Bacterial; *Gram-Negative Bacteria/ge [Genetics]; Molecular Sequence Data; Porins
Abstract:
The DNA sequence of the gene which codes for the major outer membrane porin (Omp32) of Comamonas acidovorans has been determined. The structural gene encodes a precursor consisting of 351 amino acid residues with a signal peptide of 19 amino acid residues. Comparisons with amino acid sequences of outer membrane proteins and porins from several other members of the class Proteobacteria and of the Chlamydia trachomatis porin and the Neurospora crassa mitochondrial porin revealed a motif of eight regions of local homology. The results of this analysis are discussed with regard to common structural features of porins.
