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Free keywords:
Biothermics; Macromolecular configurations; Molecular biophysics; Proteins; Biomolecular structure, configuration, conformation, and active sites [A8715B]; Biothermics [A8716]; Macromolecular configuration (bonds, dimensions) [A3620H]
Abstract:
Reports the three-dimensional structure of the thermosome from Pyrodictium occultum by random conical tilt reconstruction from electron micrographs. The reconstruction reveals a complex consisting of two rings of eight subunits each, stacked face-to-face. The subunits are kidney-shaped and composed of at least two domains. In the centre of the thermosome is a large cavity of about 6.7 nm diameter; the opening of this cavity on each face of the complex is partially blocked by a mass which appears to be weakly connected to the eight-membered ring. (29 References).
