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キーワード:
Atpases associated with a diversity of cellular; Activities; Valosine-containing protein-like atpase from; Thermoplasma acidophilum; Electron tomography; Thermoplasma acidophilum.; Sensitive fusion protein; Saccharomyces-cerevisiae; Vesicular transport; Crystal-structure; Membrane-fusion; Cell-cycle; Domain; Nsf; Microscopy; Family.; Biochemistry & Biophysics in Current Contents(R)/Life Sciences.
要旨:
Valosine-containing protein-like ATPase from Thermoplasma acidophilum is a member of the superfamily of ATPases associated with a diversity of cellular activities and is closely related to CDC48 from yeast and p97 from higher eukaryotes and more distantly to N-ethylmaleimide-sensitive fusion protein. We have used electron tomography to obtain low-resolution (2-2.5 nm) three-dimensional maps of both the whole 500 kDa complex and the N-terminally truncated valosine-containing protein-like ATPase from T. acidophilum complex lacking the putative substrate binding domain. (C) 1999 Federation of European Biochemical Societies. [References: 35]
