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  Deadly encounter: ubiquitin meets apoptosis

Jesenberger, V., & Jentsch, S. (2002). Deadly encounter: ubiquitin meets apoptosis. Nature Reviews Molecular Cell Biology, 3(2), 112-121.

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Genre: Journal Article
Alternative Title : Nat. Rev. Mol. Cell Biol.

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 Creators:
Jesenberger, V.1, Author           
Jentsch, S.1, Author           
Affiliations:
1Jentsch, Stefan / Molecular Cell Biology, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565156              

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 Abstract: The ubiquitin/proteasome pathway is the main non-lysosomal route for intracellular protein degradation in eukaryotes, It is instrumental to various cellular processes, such as cell- cycle progression, transcription and antigen processing. Recent findings also substantiate a pivotal role of the ubiquitin/proteasome pathway in the regulation of apoptosis. Regulatory molecules that are involved in programmed cell death have been identified as substrates of the proteasome. Moreover, key regulators of apoptosis themselves seem to have an active part in the proteolytic inactivation of death executors.

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Language(s): eng - English
 Dates: 2002-02
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 39049
ISI: 000173821700021
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Title: Nature Reviews Molecular Cell Biology
  Alternative Title : Nat. Rev. Mol. Cell Biol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 3 (2) Sequence Number: - Start / End Page: 112 - 121 Identifier: ISSN: 1471-0072