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  Sheet conductor model of brain slices for stimulation and recording with planar electronic contacts

Fromherz, P. (2002). Sheet conductor model of brain slices for stimulation and recording with planar electronic contacts. European Biophysics Journal with Biophysics Letters, 31(3), 228-231.

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Genre: Zeitschriftenartikel
Alternativer Titel : Eur. Biophys. J. Biophys. Lett.

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 Urheber:
Fromherz, P.1, Autor           
Affiliations:
1Fromherz, Peter / Membrane and Neurophysics, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565146              

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Schlagwörter: brain slice; field potentials; current-source density; capacitive stimulation; multielectrode array
 Zusammenfassung: Current and voltage in a brain slice are considered, taking into account the boundary conditions at the surface to an electrolyte bath and at the substrate of an electron conductor. A sheet conductor model is introduced with ohmic leak conductance to the bath and capacitive coupling to the substrate. It assigns a current-source density of neuronal activity to extracellular field potentials recorded by planar contacts, and it relates the current of planar capacitive contacts to the field potential that elicits neuronal activity. Two examples are analytically solved: the recording across a layered brain slice and the stimulation by a circular electrode. The study forms the basis for neurophysical experiments with brain slices or retinae on microelectronic chips.

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Sprache(n): eng - English
 Datum: 2002-06
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 41632
ISI: 000176827900008
 Art des Abschluß: -

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Titel: European Biophysics Journal with Biophysics Letters
  Alternativer Titel : Eur. Biophys. J. Biophys. Lett.
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 31 (3) Artikelnummer: - Start- / Endseite: 228 - 231 Identifikator: ISSN: 0175-7571