hide
Free keywords:
-
Abstract:
SUMMARY: Manual processing of DNA methylation data from bisulfite sequencing is
a tedious and error-prone task. Here we present an interactive software tool
that provides start-to-end support for this process. In an easy-to-use manner,
the tool helps the user to import the sequence files from the sequencer, to
align them, to exclude or correct critical sequences, to document the
experiment, to perform basic statistics and to produce publication-quality
diagrams.Emphasis is put on quality control: The program automatically assesses
data quality and provides warnings and suggestions for dealing with critical
sequences. The BiQ Analyzer program is implemented in the Java programming
language and runs on any platform for which a recent Java virtual machine is
available. AVAILABILITY: The program is available without charge for
non-commercial users and can be downloaded from
http://biq-analyzer.bioinf.mpi-inf.mpg.de/ CONTACT: cbock@mpi-inf.mpg.de.
