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  BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing

Bock, C., Lengauer, T., Reither, S., Mikeska, T., Paulsen, M., & Walter, J. (2005). BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinformatics, 21, 4067-4068.

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 Urheber:
Bock, Christoph1, Autor           
Lengauer, Thomas1, Autor           
Reither, Sabine, Autor
Mikeska, Thomas, Autor
Paulsen, Martina, Autor
Walter, Jörn, Autor
Affiliations:
1Computational Biology and Applied Algorithmics, MPI for Informatics, Max Planck Society, ou_40046              

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 Zusammenfassung: SUMMARY: Manual processing of DNA methylation data from bisulfite sequencing is a tedious and error-prone task. Here we present an interactive software tool that provides start-to-end support for this process. In an easy-to-use manner, the tool helps the user to import the sequence files from the sequencer, to align them, to exclude or correct critical sequences, to document the experiment, to perform basic statistics and to produce publication-quality diagrams.Emphasis is put on quality control: The program automatically assesses data quality and provides warnings and suggestions for dealing with critical sequences. The BiQ Analyzer program is implemented in the Java programming language and runs on any platform for which a recent Java virtual machine is available. AVAILABILITY: The program is available without charge for non-commercial users and can be downloaded from http://biq-analyzer.bioinf.mpi-inf.mpg.de/ CONTACT: cbock@mpi-inf.mpg.de.

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Sprache(n): eng - English
 Datum: 2006-01-312005
 Publikationsstatus: Erschienen
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 279063
Anderer: Local-ID: C125673F004B2D7B-CFB03B8E8023EC7BC12570A60052B0E4-Bock2004
 Art des Abschluß: -

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Titel: Bioinformatics
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 21 Artikelnummer: - Start- / Endseite: 4067 - 4068 Identifikator: ISBN: 13674803