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  Influence of the red blood cell Ca2+-ion concentration on the erythrocyte aggregation in stasis.

Friederichs, E., Winkler, A. H., & Tillmann, W. (1989). Influence of the red blood cell Ca2+-ion concentration on the erythrocyte aggregation in stasis. Biochemical Medicine and Metabolic Biology, 41(2), 85-92. doi:10.1016/0885-4505(89)90013-3.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-4BFD-3 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002C-4C00-2
Genre: Journal Article

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2385087.pdf (Publisher version), 501KB
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Friederichs, E., Author
Winkler, A. H.1, Author           
Tillmann, W., Author
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1Abteilung Biochemische Kinetik, MPI for biophysical chemistry, Max Planck Society, ou_578616              

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 Abstract: Ca2+ ions were transported into the cell by incubation of the erythrocyte suspension with ionophore A23187, a lipophil electric neutral ion complexing substance. Erythrocyte aggregation could be increased twice, when doubling the intracellular Ca2+-ion concentration. Our measurements lead to the suggestion that an increase of the cytoplasmatic Ca2+ ion changes the physical and/or biochemical properties of the aggregation receptors on the membrane surface, i.e., cell-protein interactions are regulated by alteration of the intracellular Ca2+-ion concentration.

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Language(s): eng - English
 Dates: 1989-04
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: DOI: 10.1016/0885-4505(89)90013-3
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Title: Biochemical Medicine and Metabolic Biology
Source Genre: Journal
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Pages: - Volume / Issue: 41 (2) Sequence Number: - Start / End Page: 85 - 92 Identifier: -