非表示:
キーワード:
asymmetric catalysis; disulfonimides; homoallylic compounds; multicomponent reactions; synthetic methods
要旨:
It takes three to make things go right: The first direct asymmetric three‐component reaction of aldehydes, carbamates, and allyltrimethylsilane leading to enantioenriched homoallylic amines has been developed using a new chiral disulfonimide catalyst (see scheme). The method employs readily available, inexpensive, and nontoxic starting materials and is applicable to both aromatic and aliphatic aldehydes.
