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  Catalytic Asymmetric Pictet-Spengler Reaction

Seayad, J., Seayad, A. M., & List, B. (2006). Catalytic Asymmetric Pictet-Spengler Reaction. Journal of the American Chemical Society, 128(4), 1086-1087. doi:10.1021/ja057444l.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0014-A470-9 Version Permalink: https://hdl.handle.net/21.11116/0000-0008-40D0-4
Genre: Journal Article

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 Creators:
Seayad, Jayasree1, Author           
Seayad, Abdul Majeed1, Author           
List, Benjamin1, Author           
Affiliations:
1Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society, Kaiser-Wilhelm-Platz 1, 45470 Mülheim an der Ruhr, ou_1445585              

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 Abstract: A catalytic asymmetric Pictet−Spengler reaction has been developed, wherein treating substituted tryptamines with an aldehyde in the presence of a catalytic amount of a chiral phosphoric acid provides the corresponding tetrahydro-β-carboline derivatives in high yields and enantiomeric excesses. The reaction works well with both aliphatic and aromatic aldehydes.

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Language(s): eng - English
 Dates: 2005-11-012006-01-042006-02-01
 Publication Status: Issued
 Pages: 2
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1021/ja057444l
 Degree: -

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Title: Journal of the American Chemical Society
  Other : JACS
  Abbreviation : J. Am. Chem. Soc.
Source Genre: Journal
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Publ. Info: Washington, DC : American Chemical Society
Pages: - Volume / Issue: 128 (4) Sequence Number: - Start / End Page: 1086 - 1087 Identifier: ISSN: 0002-7863
CoNE: https://pure.mpg.de/cone/journals/resource/954925376870