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Abstract:
CSI studies of metabolites in the human brain typically suffer from poor spatial resolution or they are restricted to substances with strong peaks that are visible at longer echo times. In this study, enhanced spectral dispersion and sensitivity at high field in combination with short echo times was utilized to measure a pure glutamate map in the ventricle region of the manlike monkey model (Macaca mulatta), instead of a sum of glutamate and glutamine. In addition, first CSI results in the occipital lobe are presented with a high spatial resolution in the millimeter range.
