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Abstract:
Activation maps acquired with perfusion-based FMRI
are known to be more specific to the parenchyma and less sensitive to
proximal draining veins compared to BOLD [1]. Here, the specificity of ASL
activation maps in the nonhuman primate was investigated at high spatial
resolution. Since the choice of labeling parameters can affect the specificity
of the measured activation, the influence of the post-labeling-delay (PLD)
and labeling-time (LT) on perfusion-based activation maps was evaluated.