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キーワード:
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要旨:
Quantitative susceptibility mapping (QSM) was performed on fMRI time-series to reconstruct maps with activation induced local susceptibility changes. A multi-step image processing algorithm was developed for filtering out unwanted temporal and spatial signal variations. The method was validated on GE-EPI BOLD-fMRI datasets acquired at 7T with 1mm isotropic resolution during the application of visual, motor and somatosensory activation paradigms. Series of high-quality phase and susceptibility maps with minimal temporal noise were reconstructed, which resulted in activation maps corresponding to estimations from the modulus data. Functional QSM (fQSM) allows for quantification of the BOLD-effect for any time-series with phase information.
