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Zusammenfassung:
Scyllo-Inositol (sI) is one of the stereoisomers of inositol yielding to a singlet resonance at a chemical shift of 3.35 ppm in 1H MR spectroscopy (MRS). This work represents the first report of sI detection in the human spinal cord, which was enabled by non-water suppressed metabolite cycled 1H MRS at 3T. The results show an increased mI/Creatine and sI/Creatine ratio compared to the brain which might be an indicator of a different metabolism in the spinal cord.