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キーワード:
Simulated moving bed Enantiomer Racemization Gradient Integrated process Reactive separation
要旨:
A new integrated 3-zone simulated moving bed (SMB) concept with internal racemization reaction was
suggested recently for the production of single enantiomers from racemic mixtures [1,2]. The process
utilizes an internal gradient to trigger the racemization within a single zone. It can deliver the pure
enantiomer and outperforms conventional technologies. In this contribution, the concept is validated
experimentally for the separation of a model system compound. The results demonstrate that the new
concept is capable of producing a single enantiomer with purity, yield and conversion of 100%.
© 2011 Elsevier B.V. All rights reserved. [accessed 2013 July 2nd]
