Investigation of interaction between DCDC2 and KIAA0319 in a large German 
dyslexia sample

Ludwig, K. U.; Roeske, D.; Schumacher, J.; Schulte-Körne, G.; König, I. R.; Warnke, A.; Plume, E.; Ziegler, A.; Remschmidt, H.; Müller-Myhsok, B.; Nöthen, M. M.; Hoffmann, P.

Local TagsRelease HistoryDetailsSummary

Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample

Ludwig, K. U., Roeske, D., Schumacher, J., Schulte-Körne, G., König, I. R., Warnke, A., et al. (2008). Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample. Journal of Neural Transmission, 115(11), 1587-1589.

Item is Released

show all hide all

Basic

show hide

Item Permalink: https://hdl.handle.net/11858/00-001M-0000-000E-939F-B Version Permalink: https://hdl.handle.net/11858/00-001M-0000-000E-93A0-5

Genre: Journal Article

Alternative Title : J. Neural Transm.

Files

show Files

Locators

show

Creators

show

hide

Creators:
Ludwig, K. U., Author
Roeske, D., Author
Schumacher, J., Author
Schulte-Körne, G., Author
König, I. R., Author
Warnke, A., Author
Plume, E., Author
Ziegler, A., Author
Remschmidt, H., Author
Müller-Myhsok, B.¹, Author
Nöthen, M. M., Author
Hoffmann, P., Author

Affiliations:
1AG Müller-Myhsok, Bertram, Florian Holsboer (Direktor), Max Planck Institute of Psychiatry, Max Planck Society, ou_1607154

Content

show

hide

Free keywords: DYX2; Doublecortin domain; Interaction; Reading; Spelling

Abstract: The dyslexia susceptibility locus DYX2 (chr. 6p21-p22) harbours two candidate genes, DCDC2 and KIAA0319. In 2006, Harold et al. reported evidence for interaction between both genes. Having previously identified a risk haplotype for dyslexia in DCDC2, but not KIAA0319, in German families, we also tested for interaction between this risk haplotype and KIAA0319. We found a nominally significant association for the quantitative dimension "word reading", the core phenotype in the study of Harold et al., which may be considered as supportive evidence.

Details

show

hide

Language(s): eng - English

Dates: Date issued: 2008-11

Publication Status: Issued

Pages: -

Publishing info: -

Table of Contents: -

Rev. Type: Peer

Identifiers: eDoc: 395629
ISI: 000260525900013

Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show

hide

Title: Journal of Neural Transmission

Alternative Title : J. Neural Transm.

Source Genre: Journal

Creator(s):

Affiliations:

Publ. Info: -

Pages: - Volume / Issue: 115 (11) Sequence Number: - Start / End Page: 1587 - 1589 Identifier: ISSN: 0300-9564