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  Design of robust flow processing networks with time-programmed responses

Kaluza, P. F., & Mikhailov, A. S. (2012). Design of robust flow processing networks with time-programmed responses. European Physical Journal B, 85(4):. doi:10.1140/epjb/e2012-20433-8.

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資料種別: 学術論文

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 作成者:
Kaluza, Pablo F.1, 著者           
Mikhailov, Alexander S.1, 著者           
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1Physical Chemistry, Fritz Haber Institute, Max Planck Society, ou_634546              

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 要旨: Can artificially designed networks reach the levels of robustness against local damage which are comparable with those of the biochemical networks of a living cell? We consider a simple model where the flow applied to an input node propagates through the network and arrives at different times to the output nodes, thus generating a pattern of coordinated responses. By using evolutionary optimization algorithms, functional networks – with required time-programmed responses – were constructed. Then, continuing the evolution, such networks were additionally optimized for robustness against deletion of individual nodes or links. In this manner, large ensembles of functional networks with different kinds of robustness were obtained, making statistical investigations and comparison of their structural properties possible. We have found that, generally, different architectures are needed for various kinds of robustness. The differences are statistically revealed, for example, in the Laplacian spectra of the respective graphs. On the other hand, motif distributions of robust networks do not differ from those of the merely functional networks; they are found to belong to the first Alon superfamily, the same as that of the gene transcription networks of single-cell organisms.

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言語: eng - English
 日付: 2012-04
 出版の状態: 出版
 ページ: 16
 出版情報: -
 目次: -
 査読: 査読あり
 識別子(DOI, ISBNなど): DOI: 10.1140/epjb/e2012-20433-8
 学位: -

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出版物名: European Physical Journal B
  その他 : Eur. Phys. J. B
種別: 学術雑誌
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出版社, 出版地: Heidelberg : Springer-Verlag Heidelberg
ページ: - 巻号: 85 (4) 通巻号: 129 開始・終了ページ: - 識別子(ISBN, ISSN, DOIなど): ISSN: 1434-6028
CoNE: https://pure.mpg.de/cone/journals/resource/954927001233