Tipping the balance toward longevity

Antebi, Adam

doi:10.1016/S1534-5807(04)00068-1

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Tipping the balance toward longevity

Antebi, A. (2004). Tipping the balance toward longevity. Developmental Cell, 6(3), 315-316. doi:10.1016/S1534-5807(04)00068-1.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-8899-8 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-889A-6

Genre: Journal Article

Alternative Title : Dev Cell

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Creators:
Antebi, Adam¹, Author

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1Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433554

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Abstract: Genetic experiments in C. elegans suggested that SIR2, an NAD-dependent protein deacetylase, acts through FOXO/DAF-16 transcription factor to prolong life. Recent studies show that mammalian SIR2 deacetylates FOXO, and may maximize survival by tempering cell death and increasing stress resistance.

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Language(s): eng - English

Dates: Date issued: 2004-03-29

Publication Status: Issued

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Identifiers: eDoc: 228591
DOI: 10.1016/S1534-5807(04)00068-1

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Title: Developmental Cell

Alternative Title : Dev Cell

Source Genre: Journal

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Pages: - Volume / Issue: 6 (3) Sequence Number: - Start / End Page: 315 - 316 Identifier: ISSN: 1534-5807