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  Modelling of signal transduction in yeast – sensitivity and model analysis

Klipp, E., & Schaber, J. (2006). Modelling of signal transduction in yeast – sensitivity and model analysis. In M. Cánovas, J. L. Iborra, & A. Manjón (Eds.), Understanding and exploiting systemy biology in bioprocesses and biomedicine (pp. 15-30). Murcia: Fundación Cajamurcia.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-8509-4 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0010-850A-2
Genre: Book Chapter

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KlippSysBiol.pdf (Any fulltext), 427KB
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 Creators:
Klipp, Edda1, Author           
Schaber, Jörg2, Author
Affiliations:
1Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433554              
2Max Planck Society, ou_persistent13              

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Free keywords: signal transduction; mathematical modelling; sensitivity analysis; parameter dependence
 Abstract: Experimental research has revealed components and mechanisms of cellular stress sensing and adaptation. In addition, mathematical modelling has proven to foster the understanding of some basic principles of signal transduction and signal processing as well as of sensitivity and robustness of information perception and cellular response. Here we review some modelling principles, results and open questions exemplified for a model organism, the yeast Saccharomyces cerevisiae.

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Language(s): eng - English
 Dates: 2006
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 309221
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Title: Understanding and exploiting systemy biology in bioprocesses and biomedicine
Source Genre: Book
 Creator(s):
Cánovas, M., Editor
Iborra, J. L., Editor
Manjón, A., Editor
Affiliations:
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Publ. Info: Murcia : Fundación Cajamurcia
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 15 - 30 Identifier: -