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  Concise and Practical Synthesis of Latrunculin A by Ring-Closing Enyne-Yne Metathesis

Fürstner, A., & Turet, L. (2005). Concise and Practical Synthesis of Latrunculin A by Ring-Closing Enyne-Yne Metathesis. Angewandte Chemie International Edition, 44(22), 3462-3466. doi:10.1002/anie.200500390.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-000F-94E3-3 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0025-B054-2
Genre: Journal Article

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 Creators:
Fürstner, Alois1, Author           
Turet, Laurent1, Author           
Affiliations:
1Research Department Fürstner, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445584              

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Free keywords: alkynes; cross-coupling; macrocycles; metathesis; natural products
 Abstract: Selective actin-binding is the most prominent biochemical property of the scarce marine natural product latrunculin A (see formula). Modern metal-catalyzed C-C bond-formation reactions, including a ring-closing enyne–yne metathesis (shown in red), now open a convenient, flexible, and productive entry to this important probe molecule for chemical biology.

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Language(s): eng - English
 Dates: 2005-02-012005-04-212005-05-30
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 265319
DOI: 10.1002/anie.200500390
ISI: 000229549100022
 Degree: -

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Title: Angewandte Chemie International Edition
  Other : Angew. Chem. Int. Ed.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH Verlag GmbH & Co. KGaA
Pages: - Volume / Issue: 44 (22) Sequence Number: - Start / End Page: 3462 - 3466 Identifier: Other: 1521-3773
CoNE: https://pure.mpg.de/cone/journals/resource/0570-0833