非表示:
キーワード:
asymmetric catalysis; epoxidation; hydrogen peroxide; ketones; organocatalysis
要旨:
Efficient, selective: The primary amine salt 1 derived from quinine efficiently catalyzes the highly enantioselective hydroperoxidation of α,β‐unsaturated ketones furnishing stable and isolable cyclic peroxyhemiketals in enantiopure form. The versatility of the peroxyhemiketals was demonstrated with the syntheses of aldols and epoxides from α,β‐unsaturated ketones and hydrogen peroxide (see scheme).
